News Release 16-Mar-2023 Antibody fragment-nanoparticle therapeutic eradicates cancer Peer-Reviewed Publication Cornell University ITHACA, N.Y.

Wiesner first developed them more than 15 years ago and, in collaboration with Bradbury, published a 2018 study that found an antibody fragment-nanoparticle hybrid to be especially effective in ...

An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression. ACS Chemical Neuroscience, 2023; DOI: 10.1021/acschemneuro.3c00455 ...

Immunosensors are widely used in immunoassays to detect antigens. One such immunosensor is a quenchbody (Q-body), which contains a modified antibody fragment with a quenched fluorescent dye. When ...

Our study shows how a small antibody fragment can block fertilization by targeting ZP2, a key protein in the outer layer of the egg that is involved in both sperm binding and blocking polyspermy." ...

KaloBios Pharmaceuticals is to receive $35 million up front from Sanofi Pasteur as part of the companies’ collaboration to develop KaloBios’ Phase II-stage antibody fragment KB001 for treating ...

In this phase 1, double-blind trial, we randomly assigned (in a 2:1 ratio) 40 patients with wild-type or variant ATTR cardiomyopathy and chronic heart failure to receive intravenous infusions of ...

Maerivoet, A., et al. (2024) Enhanced stabilisation and reduced fibril forming potential of an amyloidogenic light chain using a variable heavy domain to mimic the homodimer complex. The FEBS ...

A new study from Karolinska Institutet shows how a small antibody fragment can block fertilization by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal ...