Renal hypoperfusion occurs as a result of reduced cardiac output, resulting in the activation of the renin–angiotensin–aldosterone ... myocardial fibrosis, ventricular arrhythmias, and ...

FIGURE 2. Summary of the interventions of cardiac fibrosis. Note: CAR, chimeric antigen receptor; NLRP3: nod-like receptor protein three; RAAS: renin-angiotensin-aldosterone system; SGLT2-i: ...

The patients were treated with β-blockers (n=27), calcium-channel blockers (n=10), disopyramide (n=1), angiotensin-converting ... We demonstrate that patients with fibrosis in myectomy specimens have ...

Ang II, angiotensin II; PDGFD, platelet-derived growth factor ... The increased miR-133 could inhibit cardiac fibrosis, cardiac hypertrophy, funny currents, and cardiomyocyte apoptosis and contribute ...

During acute illness, treatment is aimed at maintaining cardiac function and suppressing the ... Due to their known effects in reducing fibrosis, spironolactone and angiotensin converting enzyme ...

A discovery offers new hope in the battle against pulmonary fibrosis, a debilitating lung condition that progressively makes it harder for patients to breathe. Scientists have pinpointed proteins in ...

Not all scars are created equal. That's the conclusion of a new study by Weizmann Institute of Science researchers: They found that two distinct types of scars, referred to as "hot" and "cold," can ...

The genetic disorder cystic fibrosis is unique because it can cause both breathing and digestive problems. Some 40,000 people in the U.S. currently have it, "though this is likely an ...

Metabolic dysfunction-associated steatohepatitis (MASH) significantly increases the risk of liver cirrhosis and ...