Figure 1: Targeted disruption of the mouse C3aR gene. Figure 3: Assessment of AHR to inhaled methacholine (MCh) in conscious mice. We immunized mice with 10 µg of OA and 1 mg of aluminium ...

further preventing anaphylatoxin C3a and C5a formation,” stated the authors. “Therefore, our findings may contribute to an improved understanding of these complex pathogenic mechanisms and ...

COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase mortality in patients. Platelets are fast responders to pathogen presence, alerting the surrounding immune cells ...

Figure 4. Proposed mechanisms of MIF in sepsis. LPS, cytokines and glucocorticoids stimulate macrophages, T cells and pituitary cells to produce MIF, resulting in rising MIF serum concentrations ...

Polymorphonuclear neutrophils (PMN) represent one of the first lines of defence against invading pathogens and are the most abundant leucocytes in the circulation. Generally described as ...

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