Living With Ankylosing Spondylitis Living With AS has ups and downs and can cause more than just physical symptoms. It can also affect your emotional health and limit your social life. Even so, you ...

I was constantly sweating." She was also retaining fluid. Elsie soon learned the cause - cardiac amyloidosis. "We used to think of it more as a rare disease," says Dr. Carly Fabrizio of Temple Health.

Prothena is laying off almost two-thirds of its workforce as the Irish biotech navigates the fallout from giving up on its failed amyloidosis drug. In May, the company announced the failure of the ...

Topline results were announced from a phase 3 study evaluating secukinumab in adults with newly diagnosed or relapsing giant cell arteritis (GCA). Secukinumab is an interleukin-17A antagonist ...

CAMBRIDGE, Mass., June 09, 2025--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNA interference (RNAi) therapeutics company, today announced that the European Commission (EC) has ...

Cardiac involvement depends on the type of amyloid disease. Systemic amyloidosis occurs in more than 10 per million person-years in the USA. It accounts for 1 in 1000 deaths in the British ...

Ankylosing spondylitis (AS) can be tough to diagnose for several reasons. Its symptoms, like back pain and fatigue, are similar to those of many other conditions. It tends to affect young people ...

Indications In the EU, AMVUTTRA ® (vutrisiran) is indicated for the treatment of: hereditary transthyretin amyloidosis in adult patients with stage 1 or stage 2 polyneuropathy (hATTR-PN).

Darzalex as monotherapy was investigated in two main studies involving multiple myeloma patients whose disease relapsed after, or was refractory to, at least two previous treatments, including a ...

Ankylosing spondylitis can create uncomfortable pain or stiffness in your back, neck, hips, and other areas of your body. We’ve learned a lot about AS in recent years but there’s still a lot ...

The current multi-center Phase 3 trial (NCT05184088) aims to further validate florbetaben (18F)'s efficacy in the diagnosis of cardiac amyloidosis, including the ATTR subtype.

Ankylosing spondylitis is a heritable form of seronegative spondyloarthritis that primarily affects the axial joints. Characteristic features of ankylosing spondylitis include chronic inflammatory ...