Figure 2: Interaction of RAGE with amyloid A fibrils, and RAGE-dependent activation of BV-2 transformed mononuclear phagocytes by SAA1.1. Figure 3: Effect of RAGE blockade on systemic amyloidosis ...

aLBPC-PPC, Université de Montpellier, INM INSERM, IRMB CHU de Montpellier, Montpellier, France bUniversité de Montpellier, Memory Research and Resources Center, Department of Neurology, Inserm INM, ...

The Smith-Lemli-Opitz syndrome (SLOS) is one of the archetypical multiple congenital malformation syndromes. The recent discovery of the biochemical cause of SLOS and ...

Cerebral amyloid angiopathy (CAA) has never been more relevant. The last 5 years have seen a rapid increase in publications and research in the field, with the development of new biomarkers for the ...

LOS ANGELES, CA, USA I June 03, 2025 I Immix Biopharma, Inc. (“ImmixBio”, “Company”, “We” or “Us” or ”IMMX”), a clinical-stage biopharmaceutical company developing cell therapies for AL Amyloidosis ...

These positive findings for NXC-201, which is a treatment for relapsed/refractory AL Amyloidosis, were presented at an oral presentation at the 2025 ASCO Annual Meeting in Chicago. The interim ...

Department of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, Germany. (L.D.W., A.O., F.a.d.S., J.S., E.G., B.M., M.G.F., N.F., F.A.) German ...

Lindsay Curtis is a health & medical writer in South Florida. She worked as a communications professional for health nonprofits and the University of Toronto’s Faculty of Medicine and Faculty of ...

It is important for the nurse to assess the extent of kidney involvement in amyloidosis and the development of the nephrotic syndrome. The nephrotic syndrome is suspected when there are high ...

Introduction: Cardiac amyloidosis (CA) is a rare form of cardiomyopathy. Most cases are diagnosed as either transthyretin amyloidosis (ATTR) or light chain amyloidosis (AL), based on the specific ...

Find more information on the Altmetric Attention Score and how the score is calculated. The authors' work was supported by grants from the Amyloidosis Research Committee, the Pathogenesis, Therapy of ...