The misunderstood story of Phineas Gage shows that we need a new way of understanding the experiences of brain injury ...

Sickle cell disease is one of the most common inherited blood disorders worldwide, with a particularly heavy burden in ...

These benefits include statistically significant and clinically relevant decreases in incidence rates in vaso-occlusive pain events and acute chest syndrome 295 and improved quality of life. 296 The ...

Gene therapy is a promising therapeutic approach to treat primary immunodeficiencies. Indeed, the clinical trial for the Wiskott–Aldrich Syndrome (WAS) that is currently ongoing at the Hannover ...

Background In patients presenting with acute cardiac symptoms, abnormal ECG and raised troponin, myocarditis may be suspected after normal angiography. Aims To analyse cardiac magnetic resonance (CMR) ...

Oesophageal atresia and/or tracheo-oesophageal fistula are relatively common malformations occurring in approximately 1 in 3500 births. In around half of the cases (syndromic oesophageal atresia), ...

CHEST’s new practice guidelines on transfusions in critically ill adults promote a more restrictive approach to RBC, FFP, and platelet transfusions.

Patients—often referred to as sickle cell warriors—face numerous health complications, including stroke, acute chest syndrome, and chronic organ damage, that lead to a significantly reduced ...

Key points A 57-year-old man presented to the emergency department with back and right upper quadrant abdominal pain that progressed to painful right leg swelling over a few days. His vital signs at ...

Happy Heart Syndrome, a rare condition, ... history of stage III gastric cancer with no history of cardiac diseases presented with acute chest pain, headache, and nausea.

Although these clinical pointers and scoring tools are invaluable, confirmatory testing (e.g., RT-PCR or rapid antigen testing) help steer the diagnosis in the correct direction.

Tuberculosis (TB) is a global disease caused by the bacillus Mycobacterium tuberculosis. In recent years, great progress has been made in care and control of drug-sensitive TB, whereas drug-resistant ...