Comment: The most frequently mutated ARVC genes are the desmosomal genes PKP2, DSG2, DSC2, JUP and DSP.Among these, PKP2 is the most prevalent mutated gene responsible for 11–51% of ARVC ...

Group I consisted of 40 consecutive patients affected by ARVC (28 men and 12 women, mean age 28 (8) years; range 14–42 years), fulfilling the established diagnostic criteria.12 ARVC patients with ...

Large Majority of PKP2-associated ARVC Patients Appear Eligible for TN-401 Gene Therapy Based on Low Rates of Preexisting Immunity to AAV9 Antibodies SAN DIEGO, April 24, 2025 (GLOBE NEWSWIRE ...