The U.S. Marines, known for their resilience and adaptability, rely on amphibious vehicles like the Amphibious Assault Vehicle (AAV) and its modern successor, the Amphibious Combat Vehicle (ACV ...

Technologies like imaged capillary isoelectric focusing (icIEF) are designed to help scientists make these products a reality by providing an orthogonal, fast, and high-resolution method for AAV ...

With this information in hand, researchers who, for instance, are developing a gene therapy to treat a muscle condition, could use the atlas to identify AAV vectors that preferentially target the ...

Takeda ended early-stage AAV work in 2023, and, earlier this year, Pfizer pulled the AAV-using hemophilia B gene therapy Beqvez from shelves. With Beqvez off the market, Pfizer now has no ...

AAV is used in 82% of viral vector-based gene therapies in the pipeline, and scaled production is critical to accelerate the transition from research to commercialization to bring gene therapies ...

Takeda is moving away from early R&D work in the AAV gene therapy and rare hematology spaces, with an unknown number of employees set to “transition out” of the pharma.

This work is published on bioRxiv in a preprint titled, “ Single-AAV CRISPR editing of skeletal muscle in non-human primates with NanoCas, an ultracompact nuclease.” NanoCas is a novel Cas ...

Asimov Launches AAV Edge, a Suite of AI Models, Host Cells, and Genetic Tools for End-to-End Gene Therapy Development High performance two-plasmid production system achieves E12 vg/mL ...

Adeno-associated virus (AAV)–mediated gene therapy has emerged as a promising treatment for hemophilia B. Data on safety and durability from 13 years of follow-up in a cohort of patients who had ...