In a recent study published in PLoS Pathogens, researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

Doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients for decades. However, in recent years, many doctors have shelved 6-TG in favour of newer drugs.

Results: Results from the TMZ and CCNU treatment arms were combined in the final analysis because there was no statistically significant difference between them. 38 patients with GBM were treated with ...

Background: Somatic mutations in vivo preferentially arise in proliferating (activated) cells.Ex vivo selection of T cells resistant to 6-thioguanine identifies T cells with in vivo ...

RECENT work on the tumour-inhibiting action of 6-thioguanine (TG) has suggested strongly that growth inhibition is correlated with the incorporation of TG into the tumour nucleic acids, and ...

Thioguanine therapy, 75 to 100 mg. per day, was reinstituted, and in 2 weeks the symptoms again disappeared. After discontinuing the drug, she remained essentially free of symptoms for 6 weeks ...