The San Francisco 49ers could potentially be without even more key pieces when they take on the Jacksonville Jaguars on Sunday.

San Francisco 49ers Pro Bowl edge rusher Nick Bosa left Sunday's game against Arizona with a right knee injury, from which he ...

Nick Bosa won't play again this season. He tore an anterior cruciate ligament in the win over the Cardinals on Sunday. The ...

San Francisco 49ers head coach Kyle Shanahan announced QB Brock Purdy's game status, detailed injury updates for QB Mac Jones, WR Jauan Jennings, and DL Nick Bosa, and highlighted the team's ...

If you told a San Francisco 49ers fan that they would be 3-0 heading into Week 4 despite missing their starting quarterback ...

SANTA CLARA — Nick Bosa’s torn ACL was a gut punch to the entire 49ers’ roster. “I’m sick. I’m so sick for him,” linebacker ...

Mykel Williams, the No. 11 overall pick in the 2025 NFL Draft out of Georgia Bulldogs, has been thrust into a starting role ...

Need for the dramatic? Just tune in to a 49ers game in 2025, apparently, as San Francisco notched another clutch win over the Arizona Cardinals 16-15 to remain unbeaten.

Defensive coordinator Robert Saleh of the San Francisco 49ers talks with Fred Warner during the game against the Seahawks at ...

Team reporter Kainani Stevens talks with San Francisco 49ers team reporter Briana Jeannel about Sunday’s 2025 Week 4 game ...

San Francisco 49ers GM John Lynch shares heartfelt support for Nick Bosa after his ACL injury and discusses potential trade moves.

The San Francisco 49ers are seeking their fifth 4-0 start in the Super Bowl era when they host the Jacksonville Jaguars ...