The San Francisco 49ers could potentially be without even more key pieces when they take on the Jacksonville Jaguars on Sunday.

San Francisco 49ers Pro Bowl edge rusher Nick Bosa left Sunday's game against Arizona with a right knee injury, from which he ...

Nick Bosa won't play again this season. He tore an anterior cruciate ligament in the win over the Cardinals on Sunday. The ...

San Francisco 49ers head coach Kyle Shanahan announced QB Brock Purdy's game status, detailed injury updates for QB Mac Jones, WR Jauan Jennings, and DL Nick Bosa, and highlighted the team's ...

If you told a San Francisco 49ers fan that they would be 3-0 heading into Week 4 despite missing their starting quarterback ...

SANTA CLARA — Nick Bosa’s torn ACL was a gut punch to the entire 49ers’ roster. “I’m sick. I’m so sick for him,” linebacker ...

Quarterback Brock Purdy returns for the San Francisco 49ers this week after missing two games with a toe injury. He was a ...

Mykel Williams, the No. 11 overall pick in the 2025 NFL Draft out of Georgia Bulldogs, has been thrust into a starting role ...

Former Chicago Bears edge rusher, Leonard, Floyd, has been touted as a trade candidate to replace the injured Nick Bosa with the 49ers.

Need for the dramatic? Just tune in to a 49ers game in 2025, apparently, as San Francisco notched another clutch win over the Arizona Cardinals 16-15 to remain unbeaten.

His season-ending UCL injury is a significant setback for the 49ers, not only because of his incredible impact on the field but also due to his leadership off it. Bosa is an instrumental presence in ...

Defensive coordinator Robert Saleh of the San Francisco 49ers talks with Fred Warner during the game against the Seahawks at ...