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eLife2d
Erythrocytosis-inducing PHD2 mutations implicate biological role for N-terminal prolyl-hydroxylation in HIF1α oxygen-dependent degradation domain
Mutations in EGLN1, the gene encoding for hypoxia-inducible factor (HIF) prolyl-4-hydroxylase 2 (PHD2), cause erythrocytosis and in rare cases the development of neuroendocrine tumors. In the presence ...
C&EN3d
In Situ Construction of Three Anion-Dependent Cu (I) Coordination Networks as Promising Heterogeneous Catalysts for Azide–Alkyne “Click” Reactions - ACS Publications
Microwave‐assisted Synthesis, Crystal Structures, and Thermal Stability of C 11 H 10 N 2 Cu 2 Br 3 and C 22 H 20 N 4 Cu 8 I 10. Zeitschrift für anorganische und allgemeine Chemie 2018 , 644 (24) , ...
C&EN5d
Tween 80−Sodium Deoxycholate Mixed Micelles: Structural Characterization and Application in Doxorubicin Delivery
The objective of the present investigation is to develop and characterize anionic mixed micelles of two biocompatible surfactants, Tween 80 (T-80) and sodium deoxycholate (NaDC), and evaluate their ...
BMJ5d
Sodium-glucose co-transporter 2 inhibitor therapy
Patients with type 2 diabetes mellitus are at a higher risk of developing heart failure compared with the healthy population. In recent landmark clinical trials, sodium-glucose co-transporter 2 (SGLT2 ...