N-methyl-D-aspartate receptors (NMDARs) are ligand-gated ion channels present at most excitatory synapses in the brain that play essential roles in cognitive functions including learning and memory ...

α-bungarotoxin (α-BTX) is a neurotoxin known to irreversibly inhibit synaptic acetylcholine release by specifically binding to nicotinic acetylcholine receptors (nAChR), which are transmembrane ion ...

and acetylcholine receptor antibody (AChR-Ab; orange triangles) from baseline during cycle 1 of the ADAPT trial of efgartigimod (at a dose of 10 mg per kilogram of body weight per week for 4 weeks ...

α7 nicotinic acetylcholine receptors (α7nAChRs), expressed in neurons and astrocytes at lower levels, have been implicated in neuroinflammatory and neurodegenerative processes associated with ...

Cytisinicline is a formulation of the plant alkaloid cytisine that, like varenicline, stimulates nicotinic acetylcholine receptors. Cytisine has been widely used in Eastern European and Asian ...