Session: Individual research reports Date: Wednesday, 28 th May, 2025 ...

Activation of the α7 nicotinic acetylcholine receptor may be therapeutically useful against acute lung injury by suppressing expression of pro-inflammatory genes.

Phase 3 clinical trial of BNC-210 in social anxiety disorder on track for topline readout in Q3 2025α7 nicotinic ...

Initiation by Merck of a Phase 2 trial in Alzheimer’s disease with partnered α7 nicotinic acetylcholine receptor PAM MK-1167 highlights company’s pipeline diversification beyond BNC210 US $15M ...

Initiation by Merck of a Phase 2 trial in Alzheimer’s disease with partnered α7 nicotinic acetylcholine receptor PAM MK-1167 highlights company’s pipeline diversification beyond BNC210 US $ ...

President and CEO of Neuphoria, Spyros Papapetropoulos, M.D., Ph.D., expressed enthusiasm over the progress, indicating that the milestone underscores the potential of α7 nicotinic acetylcholine ...

Bionomics is advancing its lead drug candidate, BNC210, an oral, proprietary, selective negative allosteric modulator of the α7 nicotinic acetylcholine receptor, for the acute treatment of Social ...

More information: Spyridon Papapetropoulos et al, BNC210, an α7 Nicotinic Receptor Modulator, in Post-Traumatic Stress Disorder, NEJM Evidence (2024). DOI: 10.1056/EVIDoa2400380 Journal ...

In a modified intent-to-treat analysis of 182 patients, treatment effects with BNC210 -- a novel α7 nicotinic acetylcholine receptor-negative allosteric modulator -- were seen as early as week 4 ...

today announced an update on the company’s α7 Nicotinic Acetylcholine Receptor (nAChR) Positive Allosteric Modulator (PAM) collaboration with MSD (known as Merck & Co., Inc., Rahway NJ ...

Three days after appointing its next CEO, Bionomics had to break the news to investors that its lead asset has flunked a phase 2 trial in acute social anxiety disorder (SAD). The candidate, dubbed ...

The α7 nicotinic acetylcholine receptor (α7nAChR) is a promising therapeutic target in neurodegenerative diseases. This study examined the effects of surgery and anesthesia on α7nAChR expression in ...