An international collaboration has published groundbreaking research, shedding light on the most significant increase in complexity in the history of life's evolution on Earth: the origin of the ...

Knockout of other components of the spliceosome or splicing regulators similarly sensitizes MTAP-deleted cells to AM-9747 treatment in vitro. In a complementary pharmacologic approach, treatment with ...

1Lewis Katz School of Medicine at Temple University, Fox Chase Cancer Center, Philadelphia, PA; ...

Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...