Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and ...

To the Editor: At the time of the publication of the first PREDIMED (Prevención con Dieta Mediterránea) trial results in 2013, 1 the relative reduction of 30% in the risk of cardiovascular events ...

Tumor lysis syndrome is a pathophysiological state that occurs when the ability of the body to maintain electrolyte–uric acid homeostasis is overwhelmed as a result of the destruction of malignant ...

In the Gates Foundation’s final chapter, it is doubling down on its wager that health can engender prosperity. That proposition must now contend with the mixed macroeconomic evidence.

The painkilling, antipyretic, and antiinflammatory properties of aspirin have been known for centuries. The understanding that aspirin targets cyclooxygenase-1 (COX-1) (also known as ...

Many AI innovations could benefit patients and clinicians. Yet medicine should heed lessons from industries in which AI adoption has resulted in reduced autonomy for workers and inferior working co ...

New AI-based software for generating patient notes purposely filters out social “chitchat,” but a primary care physician sees serious risks in that practice, for doctors and patients alike.

Michael Welsh, Jesús González, and Paul Negulescu have won the 2025 Lasker–DeBakey Clinical Medical Research Award for their roles in developing treatments for cystic fibrosis.

In this phase 3, multinational, randomized, double-blind trial, we examined the safety and efficacy of once-daily orforglipron at doses of 6 mg, 12 mg, or 36 mg, as compared with placebo (assigned in ...

Reductions in the estimated number of new HIV infections in the United States have overshadowed disconcerting trends among Latino people. Increased visibility, political will, and resources are needed ...

A 46-year-old otherwise healthy man presented with a 1-year history of occasional dysphagia to solid foods that was not accompanied by weight loss. A barium-swallow examination revealed posterior o ...

A 76-year-old retired cardiovascular nurse presented to the ED with 2 hours of chest pain triggered by severe emotional distress and associated with changes in the electrocardiogram on her smartwatch.