Congenitally corrected transposition of the great arteries (ccTGA) is a rare defect representing approximately 0.5% of all congenital heart disease. ccTGA is characterised by the combination of ...

Objectives Most patients with hypertension require more than one drug to attain recommended blood pressure (BP) targets. Initiating therapy with two agents is recommended for patients at high risk of ...

The workup of cardiac disease in patients with autoimmune disorders The range of CV manifestations of rheumatological diseases are broad and include but are not restricted to coronary artery disease ...

Prosthesis-patient mismatch (PPM) is present when the effective orifice area of the inserted prosthetic valve is too small in relation to body size. Its main haemodynamic consequence is to generate ...

Background Surgical ablation (SA) is a key treatment for atrial fibrillation (AF) patients undergoing heart surgery. However, direct comparisons between SA and non-mitral valve (non-MV) surgery alone ...

### Learning objectives In this review, we will discuss the current knowledge of heart valve disease (HVD) epidemiology, how it has changed over time and possible future trends. There are large ...

The timing of aortic valve surgery is described for patients presenting with two conditions: aortic stenosis and chronic aortic regurgitation. Aortic stenosis may be caused by rheumatic disease, a ...

Background Atrial fibrillation(AF) may be linked to increased sudden cardiac death (SCD) risk, but patients with AF are often neglected in studies on ECG risk factors for SCD. We aimed to clarify the ...

Objective We retrospectively analysed outcome data from the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study to assess the incidence and potential risk factors of sudden cardiac death (SCD) ...

Background Cancer survivors have an increased risk of heart failure, but this is balanced by the risk of death from other ...

In the context of a steadily ageing population, there is a continuous increase in the prevalence and incidence of all primary chronic conditions.1 Among the chronic conditions, heart failure (HF), ...