Background/aims To evaluate the long-term effects of treat-and-extend dosing of ranibizumab with and without navigated focal laser for diabetic macular oedema (DME). Methods This is a multicentre, ...

Impression cytology refers to the application of a cellulose acetate filter to the ocular surface to remove the superficial layers of the ocular surface epithelium. These cells can then be subjected ...

Aims To investigate the prevalence and incidence of presbyopia in an urban Chinese population. Methods 1817 subjects aged ≥35 years were identified by random cluster sampling in Yuexiu District, ...

AIMS The purpose of the study was to analyse, whether the shape and the height to base ratio in B-scan ultrasonography are appropriate to differentiate choroidal melanomas from metastases. METHODS ...

Aims To investigate the efficacy and safety of a single intracameral bevacizumab injection to improve the outcome of trabeculectomy. Methods A 12-month, prospective, randomised, double-masked, placebo ...

Aim: To clarify the intraocular pressure (IOP)-lowering profile of tafluprost, a newly synthesised prostaglandin F2α analogue, in mice. Methods: C57BL/6J, and EP1, EP2, EP3 and postaglandin F (FP) ...

Gelatinous drop-like corneal dystrophy (GDLD) is a rare autosomal recessive form of corneal dystrophy characterised by subepithelial and stromal amyloid deposits. It is relatively common in Japan. It ...

Background/Aims To compare several methods of macular hole measurement using optical coherence tomography (OCT), and to assess their predictive capability against anatomical and visual outcomes in a ...

Aims: To evaluate the clinical significance of macular hole closure types assessed by optical coherence tomography (OCT). Methods: This study involved 34 eyes of 32 patients who had undergone ...

Aim: To investigate the correlation between retinal nerve fibre layer (RNFL) thickness and optic nerve head (ONH) size in normal white subjects by means of optical coherence tomography (OCT). Methods: ...

Background/aims To compare the effectiveness and side-effect profile of two doses of interferon alpha2b (IFNα2b) eye-drops (1 million international units (IU)/ml versus 3 million IU/ml) in the ...

Cerebrospinal fluid pressure (CSFP) interacts with intraocular pressure (IOP) and blood pressure to exert a major influence upon the eye, particularly the optic nerve head region. There is increased ...