BMJ12h
AB0860 STUDY DESIGN OF ROCCELLA: A PHASE 2 CLINICAL TRIAL WITH A DISEASE-MODIFYING OSTEOARTHRITIS DRUG CANDIDATE GLPG1972/S201086
Background: Loss of articular cartilage is one of the major signs of osteoarthritis (OA). Aggrecan, the main proteoglycan component of the extracellular matrix of articular cartilage is cleaved by ...
BMJ15h
PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes
Correspondence to Dr. Nunzio Bottini, Dept. of Medicine, University of California San Diego, MC0656, La Jolla, CA 92093, USA; nbottini{at}ucsd.edu; Professor Costantino Pitzalis, William Harvey ...