The Buffalo Bills will host the New Orleans Saints at Highmark Stadium in Week 4. For this cross-conference battle between ...

The Buffalo Bills continue their 2025 NFL season with a matchup against the New Orleans Saints at home at Highmark Stadium in ...

Find single game tickets to the Buffalo Bills vs. New Orleans Saints NFL Week 4 matchup on Sunday, September 28, 2025 at ...

NFL Week 4 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the New Orleans ...

The Buffalo Bills will lock horns with the New Orleans Saints in Week 4 of the NFL season on Sunday September 28. This ...

We searched high and low for a brave soul who picked the New Orleans Saints to beat the Buffalo Bills on Sunday.

At 16.5 points, Buffalo is the heaviest favorite they've been since 2021, as they host a winless New Orleans team that just ...

The Buffalo Bills were 11.5-point favorites in Week 3, per FanDuel, and are once again expected to run away with a victory in ...

The New Orleans Saints have gotten off to quite a slow start this year, sitting at 0-3 with one of the worst rosters in football. New Orleans has flashed signs ...

Buffalo Bills defensive tackle Ed Oliver and linebacker Matt Milano will not play Sunday against the visiting New Orleans ...

Here are four things that have to happen for Kellen Moore to get his first head coaching victory and for the Saints to avoid going 0-4.

USA Today's NFL experts make their picks for a Week 4 showdown between the Buffalo Bills and New Orleans Saints ...