The Buffalo Bills continue their 2025 NFL season with a matchup against the New Orleans Saints at home at Highmark Stadium in ...

The Buffalo Bills will host the New Orleans Saints at Highmark Stadium in Week 4. For this cross-conference battle between ...

Find single game tickets to the Buffalo Bills vs. New Orleans Saints NFL Week 4 matchup on Sunday, September 28, 2025 at ...

NFL Week 4 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the New Orleans ...

The Buffalo Bills will lock horns with the New Orleans Saints in Week 4 of the NFL season on Sunday September 28. This ...

Ed Oliver was the best player on the Bills' defense the Week 1 rally over the Baltimore Ravens .. The seventh-yar defensive ...

At 16.5 points, Buffalo is the heaviest favorite they've been since 2021, as they host a winless New Orleans team that just ...

The Buffalo Bills were 11.5-point favorites in Week 3, per FanDuel, and are once again expected to run away with a victory in ...

The New Orleans Saints have gotten off to quite a slow start this year, sitting at 0-3 with one of the worst rosters in football. New Orleans has flashed signs ...

Get the best Saints vs. Bills predictions ahead of Sunday's showdown in Buffalo. Free NFL picks for September 28.

Sean McDermott's team is looking for its first 4-0 start since 2020. The Buffalo Bills certainly can't look past the winless New Orleans Saints on Sunday.

The Buffalo Bills have started their 2025 NFL season. Their next outing rounding out the first quarter of the year is against the New Orleans Saints at Highmark Stadium in Week 4.