Nick Safier and his little brother Gabe share the best ritual. When Nick, 28, leaves home and returns, his brother Gabe, 21, who has Down syndrome, gives him a big hug and a kiss on the nose.

To mark World Down Syndrome Day on March 21, Fox News contributor Tom Shillue headed to Times Square to speak with a father of a girl with Down syndrome about common misperceptions.

I’m not afraid of Down syndrome. Instead, I’m afraid of what my life might have been had we not been given my little girl Josie. She’s perfect.

"Happy World Down syndrome Day from our family to yours! 3/21 💛💙 ️," she wrote in the caption. In the two images, mom and daughter pulled funny faces as they posed for the camera.

The ad, created by an Italian Down syndrome organization called Coor Down, was released in recognition of World Down Syndrome Awareness Day, March 21. Its tagline, #AssumeICan, is being used by ...

My sister has Down syndrome. Here's how I felt watching 'Love on the Spectrum' The dating show, which recently premiered its first U.S. season, means a lot to families of a loved one with a ...