A hybrid microscope allows scientists to simultaneously image the full 3D orientation and position of an ensemble of molecules, such as labeled proteins inside cells. The microscope combines polarized ...

Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement ...

This study is the first to demonstrate that certain tRNA introns influence gene expression. Scientists have discovered that ...

This valuable work extends previous studies to convincingly show that the centromere-histone core contributes to force transduction through the kinetochore. The centromere mainly strengthens one of ...

Medically reviewed by Smita Patel, DO Duchenne muscular dystrophy (DMD) is a rare neurological condition that causes severe muscle weakness and intellectual disability. DMD is an inherited (passed ...

In  a  paper  published  on  aBIOTECH,  the  authors  revealed  the  joint  regulation  of  chromatin structure and gene expression by BMI1s, the core components of Arabidopsis PRC1, and the condensin ...

The authors uncover SRBD1 as a key mediator of these essential processes that localizes topoisomerase IIα to mitotic chromosomes. Genome structure exhibits significant plasticity, enabling it to ...

Zhang and his colleagues designed a generative AI model called ChromoGen to quickly ‘read’ DNA sequences and predict the ...

The last few years have provided us with a new level of understanding of how chromosomes are replicated, segregated and read - and how their 3D organisation influences expression of individual genes ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

A high-quality genome assembly of Silene latifolia was generated by researchers at CNRS/Université Claude Bernard Lyon 1 and ...