Activation of cGMP-dependent protein kinase (PKG) has anti-tumor effects in colon cancer cells but the mechanisms are not fully understood. This study has examined the regulation of β-catenin/TCF ...

PKG is an enzyme produced by the malaria parasite and is necessary for ... Deng W, Fivelman QL, Cummings RM, et al. (2008) Gametogenesis in malaria parasites is mediated by the cGMP-dependent ...

In central neurons, the second messenger cGMP is believed to induce long-term changes in efficacy at glutamatergic synapses through activation of protein kinase G (PKG). Stimulating nitric oxide ...

Earlier studies regarding cGMP-PKG-1 suppression of hypertrophy have primarily targeted natriuretic peptide-dependent cGMP synthesis. Cardiac deletion of the atrial natriuretic peptide (ANP ...