The San Francisco 49ers have a chance to start the season with a 4-0 record, but the Jacksonville Jaguars stand in their way.

GAME PREDICTION: The Niners run game comes alive, DeMarcus Robinson helps stabilize the pass game, and Purdy overcomes the ...

Jacksonville had the second pick in the draft; on paper, that’s an easy 49er win. On the field, this won’t be easy.

San Francisco 49ers QBs Mac Jones and Brock Purdy discussed their approach heading into Week 4 against the Jacksonville Jaguars, talked about their recovery and preparation, and highlighted how they s ...

San Francisco 49ers defensive coordinator Robert Saleh and offesnive coordinator Klay Kubiak addressed key injury updates, shared insights on player progress, and broke down the team's approach and mi ...

The Jaguars make their first West Coast trip of 2025 as they visit the San Francisco 49ers. Here are our staff predictions.

Josh Inglis' weekly NFL anytime touchdown picks include another strong showing from Davante Adams and a big-ticket TD parlay.

The San Francisco 49ers have opened the 2025 season on a strong note, sitting at 3-0 despite missing some of their biggest ...

"You could just tell he's very down to earth," said central Iowa farmer Corey Hillebo after his family was surprised by a hot meal with Brock Purdy.

Brock Purdy’s toe has improved after 2 1/2 weeks on the mend but he claimed “we’ll see” whether his two-game hiatus ends Sunday when the 49ers host Jacksonville.

San Francisco quarterback Brock Purdy is progressing well in his recovery from a toe injury and should return to the field Sunday against the Jaguars, 49ers coach Kyle Shanahan told KNBR-AM in San ...

San Francisco 49ers quarterback Brock Purdy suffered a toe injury in his team's Week 1 win over the Seattle Seahawks. The ...