In this work, we exemplify the scope and limitations of functional NA inhibition assays by showing the inhibitory activity of three well-known NAIs (oseltamivir, zanamivir and DANA), two novel ...

THE function of viral neuraminidase (N-acetylneuraminate glycohydrolase, EC 3.2.1.18) during the reproductive cycle of myxoviruses is not yet clearly defined. It was therefore considered that ...

Oseltamivir carboxylate (GS4071) and zanamivir (GG167) were obtained from GlaxoSmithKline (Uxbridge, UK) and F. Hoffmann-La Roche AG (Basel, Switzerland), respectively. N-Acetyl-2,3-dehydro-2 ...