This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

The election may mark the end of a chapter in an ongoing political crisis that could well get worse, as neither side appears likely to accept the verdict of the voters and respect the policies of the ...

Specifically, children and young adults (aged 10–24 years) with depression show subtle evidence of inflammatory dysregulation and hyperactivity of the hypothalamic–pituitary–adrenal axis. 67 ...

Innovations must, however, link the business concept to the company’s manifest capabilities. Hejazi pictures this as a two-axis graph. “The horizontal axis is about the degree to which you have ...

aFederal State Budget Institution “National Research Centre for Epidemiology and Microbiology named after Honorary Academician N F Gamaleya” of the Ministry of Health of the Russian Federation, Moscow ...

† † Department of Chemistry and Biochemistry and ‡ Department of Materials Science and Engineering, University of California, Los Angeles, California 90095, United States Article Views are the COUNTER ...