Scientists find a way to predict which malignant tumours will become aggressive and metastasise to other parts of the body.

New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came ...

Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, ...

Rhobo6, a light microscopy probe, gives scientists an unprecedented look at the extracellular matrix -- the collection of organized molecular structures that fills the spaces between cells in our ...

Researchers have developed a regenerative medicine method that successfully grafts myoblasts onto healthy muscle, boosting ...

We show here that extracellular matrix proteins interact with soluble CD95L and potentiate its pro-apoptotic activity. The cytotoxicity of supernatants from CD95L-expressing cells was increased by ...

Scientists have discovered a new way to predict which cancer tumours will become aggressive before they spread – paving the ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...