The structure of the BAX protein ... “We were thrilled to find a small molecule that targets a killer protein called BAX and stops it working,” said co-corresponding author and the Head ...

A mutation called N783Y was found to alter the SIK3 protein’s structure, hindering its ability to engage in the phosphate molecule transfer process. In this mutation, the asparagine (N ...

"Not only can it downsize future electronic devices, but its structure could also enable functions that were not even possible with silicon-based materials." Wang means that the molecule's ...

Stellar nurseries are chock-full of it. But it is difficult to detect the molecule from the ground because it glows in far-ultraviolet wavelengths that are readily absorbed by the Earth’s ...

To determine the precise structure of a new molecule, Freedman’s team uses software to analyze and process visualizations (such as those in teal and pink above) of data collected by an x-ray ...

One of these drug candidates, AVI-4516, is shown (center) bound to the active site of MPro (surrounding grey structure), where it prevents MPro from functioning. Credit: Verba Lab. Ateam at UC San ...

like small-molecule inhibitors and receptor antagonists. “If I can develop a straight-up inhibitor—[if] I have high conviction I can achieve a chemical structure that’s selective ...

Reviewing the molecule structure is essential to determine the drug type. Some drugs may be available as either non-salt (covalent) molecules or as salts (e.g., phenobarbital and sodium phenobarbital; ...

Lead researcher Professor Renier van der Hoorn (Department of Biology, University of Oxford) said, "We discovered the structure of this molecule, its biosynthesis, and its regulation—and then we ...

Sebastian Valenzuela, a doctoral student at Sahlgrenska Academy, has analyzed the molecule's structure, including by means of cryo-electron microscopy. "We demonstrate exactly where the molecule ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production. Researchers at the University of Gothenburg ...

"Otherwise, previously used protections will automatically lead to defense against the new molecule." The peptide's unique structure may also help circumvent another common bacterial defense ...