Bioreactors allow large-scale vector production in suspension or adherent 3D matrices, and are generally less labor intensive than conventional 2D systems. Here, for the first time, LV production ...

Whether prepping vector files for engraving or cleaning up ... It offers drag-and-drop tools for text, shapes, and icons, and exports high-res PNGs or PDFs you can then process in GIMP or Inkscape.

Due to its complexity, viral vector production is still evolving. Experts concur that overall yields of functional capsids containing the desired genetic payload is the biggest obstacle.

The plethora of potentially contaminating sources arising from the complexity of the viral-vector production process favors a holistic scheme for adventitious agent testing, according to Padzik. In ...

In conclusion, the SIN γ-retrovirus vector was compatible with high-titer vector production in a clinical setting, with good transduction efficiencies overall, leading to transgene expression ...

Monday, the FDA signed off on the Gilead subsidiary’s retroviral vector manufacturing facility in Oceanside, California, for commercial production of the much sought-after cell therapy component.