Aging impairs muscle and bone health, and exercise is known to mitigate this decline, partly through secreted factors. Here, the authors show that the muscle-derived factor CLCF1, which declines ...

Osteoporosis is a metabolic bone disorder characterized by progressive decline of bone mass and bone quality, leading to bone fragility and an increased risk of fracture. Osteoporosis occurs when ...

Drug May Counteract Muscle Loss and Osteoporosis After Rapid Weight Loss Feb. 10, 2025 — Rapid weight loss affects muscle mass and can increase ... local increases in bone density.

Values are compared to others of the same age and gender (Z-scores) or healthy young adults at peak bone mass (T-scores). For post-menopausal women and men age 50 and over, the result of DXA is based ...