However, the field of genetics has markedly progressed in the last decades, which resulted in improved understanding of multiple aspects of spinocerebellar ataxia type 7 retinal degeneration ...

Photoreceptor outer segments (POS) are essential for vision, and their dysfunction is associated with retinal degeneration and subsequent vision loss. Retinal organoids (ROs) have emerged as a ...

In this rat model of retinal degeneration, subretinal administration of OPGx-MERTK (1E10 vg/eye) demonstrated effective preservation of both photoreceptors and retinal function. OPGx-MERTK (AAV2 ...

State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian 116034, Liaoning, China Academy of Food Interdisciplinary Science, School of Food Science and ...

Macular atrophy was found in all patients with KCNJ13, and peripheral retinal pigment deposits were densest in KCNJ13, followed by OTX2. Minimal retinal deposition was observed in patients with ALMS1 ...

It's made up of 2 main divisions: Central nervous system. This consists of the brain and spinal cord. Peripheral nervous system. This consists of the peripheral nerves and the autonomic nerves.

OPGx-LCA5 gene therapy showed sustained improvements in cone-mediated vision, reading, and object recognition in adults with LCA5-associated retinal degeneration. The phase 1/2 trial demonstrated ...

Improvements in subjective and objective measures of efficacy observed at six months persisted for one year in patients with severe vision impairment from inherited retinal degeneration due to ...

We report the diagnosis and treatment of patients with retinal detachment and/or retinoschisis associated with optic nerve coloboma or morning glory syndrome. A retrospective review of patients ...

Flashes appearing as lightning streaks or camera-like flashes in peripheral vision typically originate from retinal traction and warrant urgent assessment. Conversely, flashes manifesting as ...

Peripheral artery disease (PAD) is a vascular disorder caused by occlusive atherosclerosis, which commonly impairs blood flow to the lower extremities. The prevalence of PAD is increasing globally ...