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Following a 14-day oral dosing regimen, Telomir-1 reversed central vision response and vision acuity, restored retinal degeneration and architecture, and significantly reduced oxidative stress ...
Reference: Sudharsan R, Murgiano L, Ahuja A, et al. Novel photoreceptor-specific promoters for gene therapy in mid-to-late stage retinal degeneration. Mol Ther. doi: 10.1016/j.ymthe.2025.05.020 This ...
Inherited retinal degenerations (IRDs) are a group of genetic disorders that lead to progressive vision loss as the light-sensing cells of the eye-the photoreceptors-die due to mutations in genes ...
Worldwide, 1 in 3,000 people suffer from IRDs, which cause progressive vision loss and retinal degeneration. So far, 326 of the roughly 20,000 human genes have been linked to these disorders.