In this stepping mechanism, the front head of a kinesin dimer must remain bound until the rear head dissociates from the microtubule, moves forward, and rebinds to the tubulin on the plus-end side of ...

A new study investigating D-dimer testing in patients who are at higher risk of pulmonary embolism (PE) has been published in the February issue of Academic Emergency Medicine (AEM), the peer ...

and three bands of even higher frequencies at the level of tubulin—the material microtubules are made of. Within each frequency another three bands of frequencies operate: a triplet of triplets.

In a recent issue of the Clinical Journal of the American Society of Nephrology, Wu and colleagues reported on the predictive value of routine D-dimer measurements for future thromboembolic events ...

Deep vein thrombosis (DVT) happens when a blood clot (thrombus) forms deep inside your vein. It usually forms in your legs. But it can happen anywhere. If DVT goes untreated, it can become life ...

In addition, the systemic coagulation and bleeding may also present as petechiae, purpura, ecchymoses, or hematomas. Ischemic damage related to thrombosis could manifest as cyanosis, as well as ...

Our findings reveal that the C-terminal region of GAS2 is essential for its dimerization, tubulin nucleation, and bundling abilities, providing significant insights into the molecular mechanisms of ...

In healthy cells, cyclin D1 is expressed during the G1 phase of the cell cycle, where it activates CDK4 and CDK6. Its dysregulation is a well-established oncogenic driver in numerous human cancers.

Recent advancements in single-molecule biophysics have been driven by breakthroughs in advanced fluorescence microscopy techniques and the development of next-generation organic fluorophores. These ...