A recent study published in the journal Nature Microbiology examines tryptophan metabolism in response to increased dietary fiber intake. Study: Dietary fibre directs microbial tryptophan ...

On May 29, 2025, Professor Sun Jinpeng's team and Professor Yu Xiao's team at Shandong University, collaborating with Professor Jiang Changtao from Peking University, Professor Pang Yanli, and ...

The relationship works bidirectionally—immune activation can alter tryptophan metabolism, potentially explaining mood changes observed during illness. Gut health maintains a complex relationship ...

All were taking a full diet supplying approximately 1 gm. of tryptophan per day. The control subjects were drawn from laboratory personnel and middle-aged persons undergoing periodic health ...

And the result “identified alterations in tryptophan metabolism, and specifically indole, that correlated with disease.” “We found that when indole is present, the mice start to develop ...

The deranged tryptophan metabolism producing excessive amounts of indole-3-acetic acid and possibly tryptamine in the malabsorption syndrome may contribute to the anemia, diarrhea and malnutrition ...

By further exploring the underlying mechanism of SIN-mediated gut microbiota regulation, the team found that tryptophan metabolites (indole-3-acrylic acid, indole-3-propionic acid, and indole-3 ...

The research highlights the complex role of tryptophan metabolism in cancer. While tryptophan is known to be metabolized into ...

New research shows how metabolic activity and thus the communication between intestinal tissue and microbiome collapses during intestinal inflammation.

This cycle impacts many other functions, including the metabolism of nutrients and your immune system (23). Several studies have shown that increasing tryptophan in the diet can improve sleep by ...

Prenatal phthalate levels in the mother's blood during pregnancy were associated with lower levels of key neurotransmitter precursors (related to tyrosine and tryptophan metabolism) important for ...

Tryptophan metabolism in the gut. In the gastrointestinal tract, tryptophan is broken down into indole, indole lactic acid (ILA), or indole propionic acid (IPA).