BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Here we asked how genetic modifications shape the dose–response curve of biosensors based on metabolite-responsive transcription factors. Using the lac system in Escherichia coli as a model system, we ...

Changes in the levels and activities of neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), have ... which revealed defects in BDNF transcription, intracellular transport ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

SPEEDWAY, Ind. — A new factor in the 109th running of the Indianapolis 500 is the hybrid system IndyCar introduced in July 2024. The hybrid system has become a buzzword in IndyCar racing ...

CNET's resident meal kit expert David Watsky tested 25 meal kits, including Factor, a few years ago to find the best of the best. David found Factor to be mostly tasty and healthy with just a few ...

Another significant factor for China was Trump's public berating of Ukrainian President Volodymyr Zelenskiy in February, said one of the sources, adding that any unscripted hostile interaction ...

The government has insisted it will not reverse cuts to winter fuel payments, despite growing calls within Labour ranks for a rethink on the policy. Calls within the party for the cuts to be ...

Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar tudósok krt. 2, 1117 Budapest, Hungary National Drug Research and Development Laboratory, HUN-REN Research ...

To put that in perspective, it nears proprietary transcription models such as OpenAI ... The performance benchmark is measured at an RTFx (Real-Time Factor) of 3386.02 with a batch size of ...

Elsewhere, President Trump is having a more complex impact. By Matina Stevis-Gridneff Reporting from Toronto The Trump factor is shaping global politics, one election at a time — just not ...