The precise use of immunotherapy agents in locally advanced head and neck squamous cell carcinoma has not been clearly delineated, even in phase 3 trials. Although immunotherapy has emerged as an ...

Conventional NAT for locally advanced rectal cancer involves the concurrent administration of radiation and radiosensitizing agents. Typically, patients receive radiation therapy ... neoadjuvant CRT: ...

Fokas E, Schlenska-Lange A, Polat B, et al. Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for patients with locally advanced rectal cancer: long-term ...

A total neoadjuvant ... by consolidation chemotherapy is strongly recommended for patients with rectal cancer for whom NOM is a priority. Selection of RT dose-fractionation regimen, therapy ...

LCCRT results in higher two-year organ preservation and lower 2-year local regrowth compared with short-course radiation therapy. (HealthDay News) — For patients with locally advanced rectal ...

In a recent prospective observational cohort study published in eClinicalMedicine, researchers evaluated a modified regimen of total neoadjuvant ... Rectal Cancer and Preoperative Induction ...

Purpose/objective(s): To evaluate rates of clinical complete response (cCR), surgery-free survival, permanent ostomy-free survival, and factors associated with these outcomes in patients treated with ...

And most recently we've had the era of total neoadjuvant ... are we turning rectal cancer into anal cancer? Maybe, in some ways. And we also know that induction therapy in anal cancer didn't ...

Many patients with locally advanced rectal cancer ... by consolidation chemotherapy (n=166). Among the 304 patients restaged a median of 7.8 weeks after finishing total neoadjuvant therapy ...

“The strategy is now investigated in rectal cancer for tailored management according to response to induction modified FOLFIRINOX.” A move toward total neoadjuvant therapy in rectal cancer has ...