This toad can get you high—really, really high. Poachers have taken notice. As people turn to psychedelic drugs to treat depression and anxiety, the Sonoran Desert toad has become a target of ...

Pharmacologists had known the Sonoran desert toad could make 5-MeO-DMT, but it wasn’t until 1983 that Ken Nelson, a reclusive artist who lived in a decommissioned missile base in North Texas ...

When "Frog and Toad" books hit shelves over 50 years ago, critics couldn't have guessed they would become pop culture icons. Here's how it happened.

The Sonoran desert toad secretes a potent toxin that can make people sick. Despite the risks, some people have discovered that the toad's toxic secretions contain a powerful hallucinogenic.

The rare toad species produces a venom known as 5-MeO-DMT, an extremely powerful natural psychedelic that's around four to six times more potent than its better-known cousin DMT (dimethyltryptamine).

Biologists have rediscovered the "starry night" harlequin toad in Colombia for the first time in nearly three decades after the species was largely wiped out by a deadly fungal pathogen. The toad ...

Rangers in northeastern Australia were astonished when they stumbled across what may be the largest toad on record, weighing in at nearly 6 pounds. Dubbed “Toadzilla” by the rangers, the 2.7 ...

The tiny Santa Marta harlequin toad (Atelopus laetissimu s), which is just 4 centimetres long, can cling to the back of a female for five months without feeding until the pair are ready to mate.