The generation of multiple microenvironments in the thymus, such as the cortex and the medulla, requires crosstalk signals from developing thymocytes. Lympho–stromal interactions in multiple ...

Figure 3: Medulla–cortex re-organization after implantation of thymus epithelial grafts in vivo. Figure 4: Medullary islets arise in thymus stromal cell grafts generated from two different donor ...

Mainly composed of epithelial cells, lymphocytes, and dendritic cells, the thymus comprises two parts – medulla and cortex. The epithelial cells, known as TECs (thymic epithelial cells), are ...

The thymus is a soft gland with two lobes. Each lobe has a central par, known as the medulla, and an outer part, known as the cortex. It is large in infants and young children, but it decreases in ...

showed how the ratio of compartments in the thymus—known as the cortex and the medulla—changes with age. The researchers showed that structures called Hassall's bodies appear early during ...

The thymus is roughly divided into two main regions, the medulla and the cortex. It has previously been unclear whether the cortex is involved in negative selection, or whether this process is ...

Lobules have two distinct areas: A dense outer cortex that is rich in actively dividing T-cells; An inner medulla, which is much paler in colour and functions as an area of T-cell maturation. In ...

The cells in the medulla region of the thymus have a straightforward task: they are programmed to randomly display bouquets of proteins characteristic of various bodily tissues in order to "train ...

The first 3D images of a whole human thymus have been created using a specialized ... Hassall's bodies occupy a large fraction of thymic medulla, suggesting they might play a role in regulating ...