Herein, a hand-drawing paper-based bipolar electrode (BPE) electrochemiluminescence (ECL) platform for M.SssI methyltransferase (M.SssI MTase) assay was proposed via employing high electrocatalytic Pt ...

ABSTRACT GENETICS Polymorphism of the catechol-O-methyltransferase gene in Han Chinese patients with psoriasis vulgaris Lin Gao 1 * Hong Li 1 * Kai Li 1 * Zhu Shen 1 Ling Liu 1 Chunying Li 1 Zhengdong ...

Genetic alterations that have been studied for use in personalizing cancer medicine include: CYP polymorphisms, UGT1A1 polymorphisms, thiopurine methyltransferase (TPMT) polymorphisms ...

This study aimed to critically appraise the current level of economic evidence available for thiopurine S-methyltransferase (TPMT) testing of thiopurine drugs, such as azathioprine. Six economic ...

Indeed, there is already application of pharmacogenomic research in paediatric oncology practice in the UK, with treatment of acute lymphoblastic leukaemia using the standard treatment protocol (UKALL ...

Shared mechanisms of METTL3 and METTL14 in heart development and sarcomere gene regulation through methyltransferase activity. A and B, Immunofluorescence staining demonstrated effective deletion of ...

There is evidence in support of the use of azathioprine in steroid dependent ulcerative colitis patients, confirming the steroid sparing effect of azathioprine The use of azathioprine or ...