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The efficacy of this model is verified on an established benchmark protein ... calibrated structure factor functions for each constituent element of the model are constructed to produce theoretical ...
Structure of a thrombospondin C‐terminal fragment reveals a novel calcium core in the type 3 repeats
Disruption of the hairpin structure of T3 repeats 6 and 7 decreases protein secretion and stability ... are predicted to disrupt the tertiary structure of the T3–CTD assembly. We have determined the ...
These are precision polymers, and they form primary, secondary, and tertiary structures ... Amyloid fibrils are a secondary structure of protein, a class of protein aggregate.
MULTICOM4 is an advanced protein structure prediction system built on AlphaFold2 and 3. It achieved remarkable success in the 16th world-wide Critical Assessment of Techniques for Protein Structure ...
Furthermore, it is likely that the model will be a template for the tertiary structure of many homologous proteins across ... buried upon binding is ∼200 Å 2 and applies to both the protein and the ...
The protein A10 ... interest in the structure of poxvirus core proteins, there remains a drought of experimentally determined structures. The team utilized the revolutionary AlphaFold software, which ...
We present a deep learning-based predictor of protein tertiary structure that uses only a multiple sequence alignment (MSA) as input. To date, most emphasis has been on the accuracy of such deep ...
To solve this problem, we propose a graph neural network (GNNGO3D) that combines the three-dimensional structure and functional hierarchy learning. GNNGO3D simultaneously uses three kinds of ...
Tertiary lymphoid organs (TLOs ... Importantly, we uncovered that TLO structure cells, such as follicular helper T cells and germinal center B cells, present in all remodeled vessels. Among myeloid ...
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