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Phosphorylation enables tau protein to form reversible droplets, offering insights into early Alzheimer's
In a study published in the Journal of the American Chemical Society, scientists explore how a brain protein called tau changes its behavior when a small chemical group called a phosphate attaches to ...
Researchers have discovered that newborns have high levels of the tau protein, which is elevated in older people with Alzheimer’s disease, but that it causes them no harm. The discovery opens the door ...
Having a father with Alzheimer's disease may be tied to a greater spread of tau protein in the brain
While some studies have suggested that having a mother with Alzheimer's disease may put you more at risk of developing the disease, a new study finds that having a father with the disease may be tied ...
This Brush Up is sponsored by Quanterix. Learn more about tau biomarkers and clinical applications. Tau is a flexible protein that stabilizes the internal structure of neurons and supports ...
Prions transmit their abnormally folded shape onto other proteins. Researchers designed a synthetic fragment of the tau protein that exhibits prion-like behavior. Misfolded tau proteins are the ...
A complementary drug to combat Alzheimer's disease could target a specific part of the nerve cell protein tau. This is the finding of research from the University of Gothenburg, which also offers a ...
Researchers have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus represents a target for future ...
Tau protein is a microtubule-associated protein, widely present in the central nervous system. It plays a key role in maintaining and regulating the structure and function of neurons. In ...
Researchers at the University of Pittsburgh have devised a biomarker test that can spot small amounts of clumping tau protein in the brain and cerebrospinal fluid, which lead to Alzheimer's disease.
Mapping Interactions of Alzheimer’s-related Tau Protein Reveals Pathway for New Potential Treatments
The dementia associated Tau protein — known for its role in microtubule regulation — has now been found to also play important roles in the nerve signaling and mitochondrial function in the brain. A ...
When proteins are made in a cell, they start out as strings of amino acids, which have to be folded into the correct, three-dimensional shape so they will function properly. Misfolded proteins can ...
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