They found that only p-tau, not regular tau, could spontaneously form tiny droplets—micrometers in size—through a process known as liquid–liquid phase separation (LLPS), which is similar to ...

Islam, T., et al. (2025). Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer’s disease. Nature Medicine.

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells ...