The tau protein, which, when it becomes toxic, can lead to memory loss and cognitive decline. Researchers are now focusing on two main strategies to combat tau buildup: ...

Ultimately, Han and her team focused on a short segment of tau, dubbed jR2R3, which is just 19 amino acid segments in length. The segment contains a mutation called P301L, commonly found in many ...

A new study has somewhat redeemed the tau protein, which up to now has been associated with the development of Alzheimer’s disease. Turns out, the protein has a ‘good guy’ role, helping to ...

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One dose of a new treatment, delivered by nasal spray, clears away build-ups of the toxic tau protein associated with Alzheimer’s disease from inside brain cells, improving memory, according to ...

Preventing Tyr29 phosphorylation attenuates tau pathology, but TYK2 expression aggravates pathology in P301S mice. Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01777-2 ...

Key protein identified for understanding and treating Alzheimer's disease Date: March 2, 2025 Source: University of Cologne Summary: Researchers have identified a specific form of the tau protein ...

A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, reveals that the protein Tau – a key ...

Tsai's team, though, had already been studying the protein's role in Alzheimer's. In September of 2023, the team published an analysis of the brains of 427 people.

Until now, scientists did not fully understand what tau protein aggregates were doing in the brain's blood vessels.To uncover the mystery, Dr. Fossati and graduate student Roberto Guzmán ...