Source Reference: Islam T, et al "Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer's disease" Nat Med 2025; DOI: 10.1038/s41591-024-03400-0.

"Tau has long been known to be associated with neuronal dysfunction in the brain in Alzheimer's disease and other neurological disorders, but recent studies have shown that the protein also ...

A new study has somewhat redeemed the tau protein, which up to now has been associated with the development of Alzheimer’s disease. Turns out, the protein has a ‘good guy’ role, helping to ...

Tau tangles typically form years after the formation of another protein called amyloid, which creates plaques in the brain and is one of the first hallmarks of Alzheimer’s. The greater the ...

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells ...

One exam, a tau PET scan, relies on a radioactive tracer injected into the body to visualize tau protein in the brain. But it’s not often used in routine clinical practice because it’s ...

Scientists have developed a new drug that targets two key regions of the tau protein, a major contributor to Alzheimer’s disease. The drug, a peptide inhibitor called RI-AG03, successfully ...

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.

Neurology > Alzheimer's Disease Alzheimer's Relationship With Menopause Explored — Tau buildup may be influenced by late hormone therapy or early menopause, studies suggest ...

Tsai's team, though, had already been studying the protein's role in Alzheimer's. In September of 2023, the team published an analysis of the brains of 427 people.

A study of 48 post-mortem brains found a protein that appears to protect brain cells from Alzheimer's — even in people who had significant amounts of amyloid plaques in their brains.