Tau-PET imaging detects tau protein accumulation, enabling earlier and more accurate Alzheimer's diagnosis, even before symptoms appear. In individuals with both tau and amyloid proteins, ...

Our study is an important step toward better understanding how tau relates to cognition in diverse populations and has important implications for future clinical trials that aim to target tau.” The ...

Tau-PET : Future of Alzheimer's patients Value of imaging to detect the presence of tau protein in the brain to predict cognitive decline due to Alzheimer's disease ...

image: Tau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzheimer’s ...

PET imaging with specific tau radiotracers provides information on the progression of the tau burden, which can help to assess disease activity, determine treatment, and predict therapeutic outcomes.

A novel PET imaging approach has revealed distinct patterns of brain inflammation in patients with progressive apraxia of speech (PAOS), a rare neurodegenerative disorder that affects speech planning.

Researchers used PET imaging and proteomic analysis of cerebrospinal fluid to study amyloid β and tau tangle loads in Alzheimer's patients, identifying 127 proteins linked to disease progression.

Fast Track Designation Granted for use in patients being evaluated for Alzheimer's Disease, Progressive Supranuclear Palsy, or Corticobasal Degeneration ...

Higher education appeared to protect against tau accumulation during the amyloid-negative stages of Alzheimer's disease but was associated with accelerated tau accumulation in amyloid-positive stages, ...

Based on this review, 17 clinical scenarios were developed in which amyloid or tau PET may be considered. The researchers found that 7 scenarios were rated as appropriate, 2 as uncertain, and 8 as ...

Plasma eMTBR-tau243 shows a strong correlation with tau pathology and cognitive decline, offering a less invasive alternative to tau-PET imaging. Study: Plasma MTBR-tau243 biomarker identifies tau ...

Researchers at the Keck School of Medicine developed a tau PET imaging cut-point to identify early Alzheimer’s signs. The cut-point distinguished cognitive impairment in Hispanic and non-Hispanic ...