Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth—a key process in the origin of life.

To download the The Cancer Genome Atlas (TCGA)-BLCA data, we used the TCGAbiolinks (version 2.28.0) R package and retrieved the normalized expression RNA-seq data for bladder patients from the ...

Trinucleotide substrates under pH–freeze–thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme. Nature Chemistry, 2025; DOI: 10.1038/s41557-025-01830-y ...

RNA plays a key role in protein synthesis. My team and I were curious about whether RNA might actively participate in fixing double-strand breaks as a first line of defense. To explore this, we ...

More information: Jiangle Liu et al, RNA codon expansion via programmable pseudouridine editing and decoding, Nature (2025). DOI: 10.1038/s41586-025-09165-x ...