Antinuclear antibody negativity virtually excludes lupus, so avoid “just in case” testing; instead, order complements C3 and C4 and anti-double-stranded-DNA when flare is suspected, as ...

Global Burden of Depression or Depressive Symptoms in Children and Adolescents A Systematic Review and Meta-Analysis. Journal of Affective Disorders, 354, 553-562.

Lupus can be debilitating and sometimes deadly for the 3 million people who have it. A treatment called CAR T appears to stop it in its tracks.

AA can be a complication of systemic lupus erythematosus (SLE), an autoimmune disease characterized by widespread inflammation and tissue damage across various organs (1). The development of aplastic ...

The systematic and local manifestations of these conditions are compounded by the normal aging process and influence the physical therapy management of older adults with arthritis.

However, for the vast majority of lupus flares the initial treatment has to be systemic glucocorticoids. For most manifestations, prednisone at 0.25–0.5 mg/kg body weight (or equivalent) is ...