Deep in the human brain, a very specific kind of cell dies during Parkinson’s disease. For the first time, researchers have sorted large numbers of human brain cells in the substantia nigra into ...

In a recent study published in Progress in Neurobiology, researchers discover that the substantia nigra of individuals with Parkinson’s disease had a higher concentration of pheomelanin, as well ...

After stereotactic injection of ATB NPs into the substantia nigra of PD mice, the ATB NPs anchored to the surface of dopaminergic neurons via the TRPV1 antibody. Under 808 nm pulsed near-infrared ...

13 May 2022 The death of dopaminergic neurons in the substantia nigra is the defining feature of Parkinson’s disease, but not all neurons in the region suffer this fate. Why do some wither while ...

Scientists have long known that Parkinson’s—a progressive, neurodegenerative condition that currently affects about 1 million people in the United States—is associated with a die-off of ...

Alpha-synuclein shown by positive staining (brown) in a Lewy body in the substantia nigra of a patient with Parkinson's disease. (Marvin 101/ CC BY-SA 3.0/ Wikimedia Commons) ...

Steeling for a Possible Iron-Parkinson Connection Courtesy of Kurt Jellinger IF IT ONLY WERE ELEMENTARY: Element distribution found by energy dispersive x-ray analysis in neuromelanin from nigral ...

The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...