ARV-102 is an oral, brain-penetrant investigational PROTAC designed to degrade LRRK2, which is a large, multidomain scaffolding kinase. Increased activity, scaffolding, and expression of LRRK2 have ...

St. Cloud co-head wrestling coach Scot Davis has been coaching for a 49 years between junior high, high school and college. Within those 49 years, he's coached at 15 different schools. On Thursday ...

*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration ...

The best comedians in Toronto, all on one lineup, on ONE Friday night! Featuring: NOUR HADIDI (What We Do in the Shadows, Roast Battle Canada), MEG MACKAY (Don't Even, JFL, Acting Good), ADA NICOLLE ...

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In another season where they lost close battles several times, including five one-point margin losses, the Owatonna boys soccer team ended their regular season on a high note as they beat the ...

We're going to give you the quick version of what you need to know about Streamlight's TLR weapon-mounted lights, as they are some of the most popular models out there. In other words, a bit of LIGHT ...

Width x Height x Depth (without stand) 1446.1 mm x 827.9 mm x 46.9 mm Width x Height x Depth (with stand) 1446.1 mm x 913.4 mm x 353.5 mm ...

I was in a dilemma when purchasing the product since the brand is not that we'll known amongst others. But, I must say, I am pretty amazed looking at the picture quality and the audio output. Gives me ...

Highlights from football games around the area, including: North Iowa vs. Riceville and Iowa Falls-Alden vs. Charles City. Plus, our Play of the Week. Highlights from football games around the area, ...