A scalable chemical method to control phosphorothioate chirality demonstrates its impact on the efficacy of antisense oligonucleotides. Whereas stereochemical purity in drugs has become the ...

It has been a longtime cherished interest to synthesize polyacetylene (PA) with ultimate control over the conjugation length as well as the stereochemistry. Scientists from China now make it ...

Permeability selection of biologically relevant membranes matches the stereochemistry of life on Earth. PLOS Biology, 2025; 23 (5): e3003155 DOI: 10.1371/journal.pbio.3003155 ...

Researchers have developed a glycan identification method based on nanopore single-molecule sensing through a glycan derivatization strategy.